Mycophenolic Acid for Topical Immunosuppression in Vascularized Composite Allotransplantation: Optimizing Formulation and Preliminary Evaluation of Bioavailability and Pharmacokinetics

Mycophenolic acid (MPA), is the active form of the ester prodrug mycophenolate mofetil (MMF). MMF is an FDA approved immunosuppressive drug that has been successfully used in systemic therapy in combination with other agents for the prevention of acute rejection (AR) following solid organ transplant...

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Dettagli Bibliografici
Pubblicato in:Front Surg
Autori principali: Feturi, Firuz G., Weinstock, Matthias, Zhao, Wenchen, Zhang, Wei, Schnider, Jonas T., Erbas, Vasil E., Oksuz, Sinan, Plock, Jan A., Rohan, Lisa, Spiess, Alexander M., Ferreira, Lydia M., Solari, Mario G., Venkataramanan, Raman, Gorantla, Vijay S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Surgery
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954844/
https://ncbi.nlm.nih.gov/pubmed/29868602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fsurg.2018.00020
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