Mycophenolic Acid for Topical Immunosuppression in Vascularized Composite Allotransplantation: Optimizing Formulation and Preliminary Evaluation of Bioavailability and Pharmacokinetics

Mycophenolic acid (MPA), is the active form of the ester prodrug mycophenolate mofetil (MMF). MMF is an FDA approved immunosuppressive drug that has been successfully used in systemic therapy in combination with other agents for the prevention of acute rejection (AR) following solid organ transplant...

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Опубликовано в: :Front Surg
Главные авторы: Feturi, Firuz G., Weinstock, Matthias, Zhao, Wenchen, Zhang, Wei, Schnider, Jonas T., Erbas, Vasil E., Oksuz, Sinan, Plock, Jan A., Rohan, Lisa, Spiess, Alexander M., Ferreira, Lydia M., Solari, Mario G., Venkataramanan, Raman, Gorantla, Vijay S.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Surgery
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954844/
https://ncbi.nlm.nih.gov/pubmed/29868602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fsurg.2018.00020
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