Mycophenolic Acid for Topical Immunosuppression in Vascularized Composite Allotransplantation: Optimizing Formulation and Preliminary Evaluation of Bioavailability and Pharmacokinetics

Mycophenolic acid (MPA), is the active form of the ester prodrug mycophenolate mofetil (MMF). MMF is an FDA approved immunosuppressive drug that has been successfully used in systemic therapy in combination with other agents for the prevention of acute rejection (AR) following solid organ transplant...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Surg
Auteurs principaux: Feturi, Firuz G., Weinstock, Matthias, Zhao, Wenchen, Zhang, Wei, Schnider, Jonas T., Erbas, Vasil E., Oksuz, Sinan, Plock, Jan A., Rohan, Lisa, Spiess, Alexander M., Ferreira, Lydia M., Solari, Mario G., Venkataramanan, Raman, Gorantla, Vijay S.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Surgery
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954844/
https://ncbi.nlm.nih.gov/pubmed/29868602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fsurg.2018.00020
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