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The Effect of Selective c-MET Inhibitor on Hepatocellular Carcinoma in the MET-Active, β-Catenin-Mutated Mouse Model
Simultaneous mutations in CTNNB1 and activation of c-MET occur in 9%–12.5% of patients with hepatocellular carcinoma (HCC). Coexpression of c-MET-V5 and mutant β-catenin-Myc in mouse liver by sleeping beauty transposon/transposase and hydrodynamic tail vein injection (SB-HTVI) led to the development...
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| Vydáno v: | Gene Expr |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cognizant Communication Corporation
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5954626/ https://ncbi.nlm.nih.gov/pubmed/29409568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221618X15174108894682 |
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