The Effect of Selective c-MET Inhibitor on Hepatocellular Carcinoma in the MET-Active, β-Catenin-Mutated Mouse Model

Simultaneous mutations in CTNNB1 and activation of c-MET occur in 9%–12.5% of patients with hepatocellular carcinoma (HCC). Coexpression of c-MET-V5 and mutant β-catenin-Myc in mouse liver by sleeping beauty transposon/transposase and hydrodynamic tail vein injection (SB-HTVI) led to the development...

Full description

Saved in:
Bibliographic Details
Published in:Gene Expr
Main Authors: Zhan, Na, Michael, Adeola Adebayo, Wu, Kaiyuan, Zeng, Gang, Bell, Aaron, Tao, Junyan, Monga, Satdarshan P.
Format: Artigo
Language:Inglês
Published: Cognizant Communication Corporation 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954626/
https://ncbi.nlm.nih.gov/pubmed/29409568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/105221618X15174108894682
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items