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Fast-Folding Pathways of the Thrombin-Binding Aptamer G-Quadruplex Revealed by a Markov State Model

G-quadruplex structures participate in many important cellular processes. For a better understanding of their functions, knowledge of the mechanism by which they fold into the functional native structures is necessary. In this work, we studied the folding process of the thrombin-binding aptamer G-qu...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Bian, Yunqiang, Song, Feng, Cao, Zanxia, Zhao, Liling, Yu, Jiafeng, Guo, Xinlu, Wang, Jihua
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954565/
https://ncbi.nlm.nih.gov/pubmed/29642024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.02.021
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