Mapping the affinity landscape of Thrombin-binding aptamers on 2΄F-ANA/DNA chimeric G-Quadruplex microarrays

In situ fabricated nucleic acids microarrays are versatile and very high-throughput platforms for aptamer optimization and discovery, but the chemical space that can be probed against a given target has largely been confined to DNA, while RNA and non-natural nucleic acid microarrays are still an ess...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Lietard, Jory, Abou Assi, Hala, Gómez-Pinto, Irene, González, Carlos, Somoza, Mark M., Damha, Masad J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Chemical Biology and Nucleic Acid Chemistry
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389548/
https://ncbi.nlm.nih.gov/pubmed/28100695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1357
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