The Anti-neuroinflammatory Activity of Tectorigenin Pretreatment via Downregulated NF-κB and ERK/JNK Pathways in BV-2 Microglial and Microglia Inactivation in Mice With Lipopolysaccharide

The activation of microglia is decisively involved with the neurodegeneration observed in many neuroinflammatory pathologies, such as multiple sclerosis, Parkinson’s disease, and Alzheimer’s disease. Tectorigenin (TEC) is an isoflavone isolated from various medicinal plants, such as Pueraria thunber...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Principais autores: Lim, Hye-Sun, Kim, Yu Jin, Kim, Bu-Yeo, Park, Gunhyuk, Jeong, Soo-Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954245/
https://ncbi.nlm.nih.gov/pubmed/29867470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00462
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