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Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion
Mutations and genetic alterations are often sequentially acquired in various biological and pathological processes, such as development, evolution, and cancer. Certain phenotypes only manifest with precise temporal sequences of genetic events. While multiple approaches have been developed to model t...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5954137/ https://ncbi.nlm.nih.gov/pubmed/29765043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04158-z |
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