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Ripply2 recruits proteasome complex for Tbx6 degradation to define segment border during murine somitogenesis
The metameric structure in vertebrates is based on the periodic formation of somites from the anterior end of the presomitic mesoderm (PSM). The segmentation boundary is defined by the Tbx6 expression domain, whose anterior limit is determined by Tbx6 protein destabilization via Ripply2. However, th...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5953544/ https://ncbi.nlm.nih.gov/pubmed/29761784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33068 |
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