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Ripply2 recruits proteasome complex for Tbx6 degradation to define segment border during murine somitogenesis

The metameric structure in vertebrates is based on the periodic formation of somites from the anterior end of the presomitic mesoderm (PSM). The segmentation boundary is defined by the Tbx6 expression domain, whose anterior limit is determined by Tbx6 protein destabilization via Ripply2. However, th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Zhao, Wei, Oginuma, Masayuki, Ajima, Rieko, Kiso, Makoto, Okubo, Akemi, Saga, Yumiko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953544/
https://ncbi.nlm.nih.gov/pubmed/29761784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33068
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