Increased Production of IL-17A-Producing γδ T Cells in the Thymus of Filaggrin-Deficient Mice

Mutations in the filaggrin gene (Flg) are associated with increased systemic levels of Th17 cells and increased IL-17A production following antigen exposure in both humans and mice. In addition to Th17 cells, γδ T cells can produce IL-17A. The differentiation of γδ T cells to either IFNγ or IL-17A-p...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Jee, Mia Hamilton, Johansen, Jeanne Duus, Buus, Terkild Brink, Petersen, Trine Hilkjær, Gadsbøll, Anne-Sofie Østergaard, Woetmann, Anders, Ødum, Niels, Thyssen, Jacob Pontoppidan, White, Andrea Jane, Anderson, Graham, Geisler, Carsten, Bonefeld, Charlotte Menné
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953325/
https://ncbi.nlm.nih.gov/pubmed/29867965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00988
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker