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Development of interleukin-17-producing Vγ2(+) γδ T cells is reduced by ICOS signaling in the thymus

Co-stimulation is an integral part of T cell signaling involved in almost all facets of T cell biology. While much is known about co-stimulation in differentiation and function of conventional αβ T cells, less is known about how co-stimulation affects the development and programming of γδ T cells. I...

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Publicat a:Oncotarget
Autors principals: Buus, Terkild Brink, Schmidt, Jonas Damgård, Bonefeld, Charlotte Menné, Geisler, Carsten, Lauritsen, Jens Peter Holst
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991387/
https://ncbi.nlm.nih.gov/pubmed/27235509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8464
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