Cobalt (II) ions and nanoparticles induce macrophage retention by ROS-mediated down-regulation of RhoA expression

Histological assessments of synovial tissues from patients with failed CoCr alloy hip prostheses demonstrate extensive infiltration and accumulation of macrophages, often loaded with large quantities of particulate debris. The resulting adverse reaction to metal debris (ARMD) frequently leads to ear...

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Vydáno v:Acta Biomater
Hlavní autoři: Xu, Jing, Yang, Junyao, Nyga, Agata, Ehteramyan, Mazdak, Moraga, Ana, Wu, Yuanhao, Zeng, Lingfang, Knight, Martin M., Shelton, Julia C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953279/
https://ncbi.nlm.nih.gov/pubmed/29649639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2018.03.054
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