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Cobalt (II) ions and nanoparticles induce macrophage retention by ROS-mediated down-regulation of RhoA expression

Histological assessments of synovial tissues from patients with failed CoCr alloy hip prostheses demonstrate extensive infiltration and accumulation of macrophages, often loaded with large quantities of particulate debris. The resulting adverse reaction to metal debris (ARMD) frequently leads to ear...

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Bibliografische gegevens
Gepubliceerd in:Acta Biomater
Hoofdauteurs: Xu, Jing, Yang, Junyao, Nyga, Agata, Ehteramyan, Mazdak, Moraga, Ana, Wu, Yuanhao, Zeng, Lingfang, Knight, Martin M., Shelton, Julia C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953279/
https://ncbi.nlm.nih.gov/pubmed/29649639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2018.03.054
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