Single-Cell Developmental Classification of B-Cell Precursor Acute Lymphoblastic Leukemia at Diagnosis Reveals Predictors of Relapse

Improved insight into cancer cell populations responsible for relapsed disease will lead to better outcomes for patients. Here, we report a single-cell study of B-cell precursor acute lymphoblastic leukemia at diagnosis that revealed hidden developmentally dependent cell signaling states uniquely as...

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Bibliografske podrobnosti
izdano v:Nat Med
Main Authors: Good, Zinaida, Sarno, Jolanda, Jager, Astraea, Samusik, Nikolay, Aghaeepour, Nima, Simonds, Erin F., White, Leah, Lacayo, Norman J., Fantl, Wendy J., Fazio, Grazia, Gaipa, Giuseppe, Biondi, Andrea, Tibshirani, Robert, Bendall, Sean C., Nolan, Garry P., Davis, Kara L.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953207/
https://ncbi.nlm.nih.gov/pubmed/29505032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4505
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