Single-Cell Developmental Classification of B-Cell Precursor Acute Lymphoblastic Leukemia at Diagnosis Reveals Predictors of Relapse

Improved insight into cancer cell populations responsible for relapsed disease will lead to better outcomes for patients. Here, we report a single-cell study of B-cell precursor acute lymphoblastic leukemia at diagnosis that revealed hidden developmentally dependent cell signaling states uniquely as...

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Publicado no:Nat Med
Main Authors: Good, Zinaida, Sarno, Jolanda, Jager, Astraea, Samusik, Nikolay, Aghaeepour, Nima, Simonds, Erin F., White, Leah, Lacayo, Norman J., Fantl, Wendy J., Fazio, Grazia, Gaipa, Giuseppe, Biondi, Andrea, Tibshirani, Robert, Bendall, Sean C., Nolan, Garry P., Davis, Kara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953207/
https://ncbi.nlm.nih.gov/pubmed/29505032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4505
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