AMPA-ergic regulation of amyloid-β levels in an Alzheimer’s disease mouse model

BACKGROUND: Extracellular aggregation of the amyloid-β (Aβ) peptide into toxic multimers is a key event in Alzheimer’s disease (AD) pathogenesis. Aβ aggregation is concentration-dependent, with higher concentrations of Aβ much more likely to form toxic species. The processes that regulate extracellu...

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Detaylı Bibliyografya
Yayımlandı:Mol Neurodegener
Asıl Yazarlar: Hettinger, Jane C., Lee, Hyo, Bu, Guojun, Holtzman, David M., Cirrito, John R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952376/
https://ncbi.nlm.nih.gov/pubmed/29764453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-018-0256-6
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