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A highly diastereoselective “super silyl” governed aldol reaction: synthesis of α,β-dioxyaldehydes and 1,2,3-triols

A highly diastereoselective approach for the synthesis of protected α,β-dioxyaldehydes derived from (Z)-tris(trimethylsilyl)silyl “super silyl” enol ethers is described. A general and highly syn-stereoselective aldol reaction directed by the “super silyl” group catalyzed by triflimide (HNTf(2)) is d...

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Dettagli Bibliografici
Pubblicato in:Chem Sci
Autori principali: Gati, Wafa, Yamamoto, Hisashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Royal Society of Chemistry 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952264/
https://ncbi.nlm.nih.gov/pubmed/29861990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03307a
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