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Stereodivergent Approach to the Avermectins Based on “Super Silyl” Directed Aldol Reactions

[Image: see text] A stereodivergent approach to the spiroketal fragment of the avermectins is described. The strategy utilizes a sequence of three aldol reactions directed by the tris(trimethylsilyl)silyl “super silyl” group. Central to this strategy is that each aldol reaction can be controlled to...

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Κύριοι συγγραφείς: Brady, Patrick B., Oda, Susumu, Yamamoto, Hisashi
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Chemical Society 2014
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120983/
https://ncbi.nlm.nih.gov/pubmed/25025525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol501327g
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