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Effects of long 5′ leader sequences on initiation by eukaryotic ribosomes in vitro

Lengthening the 5′ noncoding sequence on SP6-derived transcripts can increase their translational efficiency by an order of magnitude under some conditions of translation in reticulocyte lysates. This effect was observed upon reiterating three different synthetic oligonucleotides, the sequences of w...

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Bibliografski detalji
Izdano u:Gene Expr
Glavni autor: Kozak, Marilyn
Format: Artigo
Jezik:Inglês
Izdano: Cognizant Communication Corporation 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952206/
https://ncbi.nlm.nih.gov/pubmed/1820209
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