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Effects of long 5′ leader sequences on initiation by eukaryotic ribosomes in vitro

Lengthening the 5′ noncoding sequence on SP6-derived transcripts can increase their translational efficiency by an order of magnitude under some conditions of translation in reticulocyte lysates. This effect was observed upon reiterating three different synthetic oligonucleotides, the sequences of w...

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Detalhes bibliográficos
Publicado no:Gene Expr
Autor principal: Kozak, Marilyn
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952206/
https://ncbi.nlm.nih.gov/pubmed/1820209
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