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A short leader sequence impairs the fidelity of initiation by eukaryotic ribosomes

The functional consequences of unusually short 5′ noncoding sequences on eukaryotic mRNAs are explored here by using an in vitro transcription and translation system. As the distance of the first AUG codon from the m7G cap was decreased from 32 to 3 nucleotides, the yield of protein initiated from t...

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Publicat a:Gene Expr
Autor principal: Kozak, Marilyn
Format: Artigo
Idioma:Inglês
Publicat: Cognizant Communication Corporation 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952205/
https://ncbi.nlm.nih.gov/pubmed/1820208
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