Role of the E2 Hypervariable Region (HVR1) in the Immunogenicity of a Recombinant Hepatitis C Virus Vaccine

Current evidence supports a protective role for virus-neutralizing antibodies in immunity against hepatitis C virus (HCV) infection. Many cross-neutralizing monoclonal antibodies have been identified. These antibodies have been shown to provide protection or to clear infection in animal models. Prev...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Law, John L. M., Logan, Michael, Wong, Jason, Kundu, Juthika, Hockman, Darren, Landi, Amir, Chen, Chao, Crawford, Kevin, Wininger, Mark, Johnson, Janelle, Mesa Prince, Catalina, Dudek, Elzbieta, Mehta, Ninad, Tyrrell, D. Lorne, Houghton, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952160/
https://ncbi.nlm.nih.gov/pubmed/29540595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02141-17
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