Role of the E2 Hypervariable Region (HVR1) in the Immunogenicity of a Recombinant Hepatitis C Virus Vaccine

Current evidence supports a protective role for virus-neutralizing antibodies in immunity against hepatitis C virus (HCV) infection. Many cross-neutralizing monoclonal antibodies have been identified. These antibodies have been shown to provide protection or to clear infection in animal models. Prev...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Law, John L. M., Logan, Michael, Wong, Jason, Kundu, Juthika, Hockman, Darren, Landi, Amir, Chen, Chao, Crawford, Kevin, Wininger, Mark, Johnson, Janelle, Mesa Prince, Catalina, Dudek, Elzbieta, Mehta, Ninad, Tyrrell, D. Lorne, Houghton, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952160/
https://ncbi.nlm.nih.gov/pubmed/29540595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02141-17
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