Native Folding of a Recombinant gpE1/gpE2 Heterodimer Vaccine Antigen from a Precursor Protein Fused with Fc IgG

A recombinant strain HCV1 (hepatitis C virus [HCV] genotype 1a) gpE1/gpE2 (E1E2) vaccine candidate was previously shown by our group to protect chimpanzees and generate broad cross-neutralizing antibodies in animals and humans. In addition, recent independent studies have highlighted the importance...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Logan, Michael, Law, John, Wong, Jason Alexander Ji-Xhin, Hockman, Darren, Landi, Amir, Chen, Chao, Crawford, Kevin, Kundu, Juthika, Baldwin, Lesley, Johnson, Janelle, Dahiya, Anita, LaChance, Gerald, Marcotrigiano, Joseph, Law, Mansun, Foung, Steven, Tyrrell, Lorne, Houghton, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5165201/
https://ncbi.nlm.nih.gov/pubmed/27795422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01552-16
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