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MicroRNA-30a increases the chemosensitivity of U251 glioblastoma cells to temozolomide by directly targeting beclin 1 and inhibiting autophagy

Temozolomide (TMZ) is one of the most commonly used drugs for the clinical treatment of glioblastomas. However, it has been reported that treatment with TMZ can induce autophagy, which leads to tumor resistance and increases the survival of tumor cells. MicroRNA-30a (miR-30a) has been found to have...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Xu, Jing, Huang, He, Peng, Renjun, Ding, Xiping, Jiang, Bing, Yuan, Xianrui, Xi, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952084/
https://ncbi.nlm.nih.gov/pubmed/29805498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6007
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