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Effect of silencing S-phase kinase-associated protein 2 on chemosensitivity to temozolomide of human glioma cells U251

Objective: To examine the effect of silencing SKP2 on chemosensitivity of human glioma cells U251 to temozolomide (TMZ). Methods: Adenoviruses harbouring shRNA targeting SKP2 (i.e. Ad-shSKP2) and non-targeting scrambled shRNA (i.e. Ad-shNC) were used to infect U251 cells. The transduced cells were t...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Liu, Yue, Tang, Zhen-Gang, Yang, Jian-Quan, Zhou, Yi, Lin, Yi, Lv, Wei, Wang, Guo-Bin, Li, Cai-Li
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511802/
https://ncbi.nlm.nih.gov/pubmed/31105854
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