MicroRNA-30a Sensitizes Tumor Cells to cis-Platinum via Suppressing Beclin 1-mediated Autophagy

Autophagy is activated in cancer cells during chemotherapy and often contributes to tumor chemotherapy resistance. In this study, we characterized the role of microRNA-30a (miR-30a) in the coordination of cancer cell apoptosis and autophagy, which determines the sensitivity of cancer cells to chemot...

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Autores principales: Zou, Zhenyou, Wu, Linping, Ding, Hanying, Wang, Yang, Zhang, Yaqin, Chen, Xuejiao, Chen, Xi, Zhang, Chen-Yu, Zhang, Qipeng, Zen, Ke
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Molecular Bases of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281695/
https://ncbi.nlm.nih.gov/pubmed/22157765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.307405
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