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High expression of CXCR4 and stem cell markers in a monocrotaline and chronic hypoxia-induced rat model of pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a severe and fatal clinical syndrome. C-X-C chemokine receptor type 4 (CXCR4) is known to serve a key role in recruiting mesenchymal stem cells (MSCs) from the bone marrow. In the present study, a rat model of PAH induced by 5 weeks of chronic hypoxia and tre...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Zhang, Tingting, Kawaguchi, Nanako, Hayama, Emiko, Furutani, Yoshiyuki, Nakanishi, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952071/
https://ncbi.nlm.nih.gov/pubmed/29805477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6027
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