Mutations of NOTCH3 in childhood pulmonary arterial hypertension

Mutations of BMPR2 and other TGF-β superfamily genes have been reported in pulmonary arterial hypertension (PAH). However, 60–90% of idiopathic PAH cases have no mutations in these genes. Recently, the expression of NOTCH3 was shown to be increased in the pulmonary artery smooth muscle cells of PAH...

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Detalhes bibliográficos
Main Authors: Chida, Ayako, Shintani, Masaki, Matsushita, Yoshihisa, Sato, Hiroki, Eitoku, Takahiro, Nakayama, Tomotaka, Furutani, Yoshiyuki, Hayama, Emiko, Kawamura, Yoichi, Inai, Kei, Ohtsuki, Shinichi, Saji, Tsutomu, Nonoyama, Shigeaki, Nakanishi, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049363/
https://ncbi.nlm.nih.gov/pubmed/24936512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.58
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