Silibinin efficacy in a rat model of pulmonary arterial hypertension using monocrotaline and chronic hypoxia

BACKGROUND: C-X-C chemokine receptor type 4 (CXCR4) may be involved in the development of pulmonary arterial hypertension (PAH). CXCR4 inhibitor AMD3100 was described to have a positive effect on the prevention of pulmonary arterial muscularization in PAH models. Silibinin is a traditional medicine...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Zhang, Tingting, Kawaguchi, Nanako, Yoshihara, Kenji, Hayama, Emiko, Furutani, Yoshiyuki, Kawaguchi, Kayoko, Tanaka, Takeshi, Nakanishi, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485095/
https://ncbi.nlm.nih.gov/pubmed/31023308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1041-y
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