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Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging

Autophagy removes both functional and damaged intracellular macromolecules from cells via lysosomal degradation. Three autophagic mechanisms, namely macroautophagy, chaperone-mediated autophagy (CMA), and microautophagy, have been described in mammals. Studies in experimental systems have found macr...

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Pubblicato in:Front Aging Neurosci
Autori principali: Loeffler, David A., Klaver, Andrea C., Coffey, Mary P., Aasly, Jan O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952035/
https://ncbi.nlm.nih.gov/pubmed/29867441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00130
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