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Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging

Autophagy removes both functional and damaged intracellular macromolecules from cells via lysosomal degradation. Three autophagic mechanisms, namely macroautophagy, chaperone-mediated autophagy (CMA), and microautophagy, have been described in mammals. Studies in experimental systems have found macr...

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Bibliografische gegevens
Gepubliceerd in:Front Aging Neurosci
Hoofdauteurs: Loeffler, David A., Klaver, Andrea C., Coffey, Mary P., Aasly, Jan O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952035/
https://ncbi.nlm.nih.gov/pubmed/29867441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00130
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