Increased Oxidative Stress Markers in Cerebrospinal Fluid from Healthy Subjects with Parkinson’s Disease-Associated LRRK2 Gene Mutations

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most frequent cause of inherited Parkinson’s disease (PD). The most common PD-associated LRRK2 mutation, G2019S, induces increased production of reactive oxygen species in vitro. We therefore hypothesized that individuals with PD-ass...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Loeffler, David A., Klaver, Andrea C., Coffey, Mary P., Aasly, Jan O., LeWitt, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376564/
https://ncbi.nlm.nih.gov/pubmed/28420983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00089
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados