Elevated levels of cerebrospinal fluid α-synuclein oligomers in healthy asymptomatic LRRK2 mutation carriers

Mutations in the leucine-rich repeat kinase 2 gene are the most common cause of autosomal dominant Parkinson’s disease (PD). To assess the cerebrospinal fluid (CSF) levels of α-synuclein oligomers in symptomatic and asymptomatic leucine-rich repeat kinase 2 mutation carriers, we used enzyme-linked i...

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Detalhes bibliográficos
Main Authors: Aasly, Jan O., Johansen, Krisztina K., Brønstad, Gunnar, Warø, Bjørg J., Majbour, Nour K., Varghese, Shiji, Alzahmi, Fatimah, Paleologou, Katerina E., Amer, Dena A. M., Al-Hayani, Abdulmonem, El-Agnaf, Omar M. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174885/
https://ncbi.nlm.nih.gov/pubmed/25309429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2014.00248
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