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CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers

BACKGROUND: Asymptomatic carriers of leucine-rich repeat kinase 2 (LRRK2) gene mutations constitute an ideal population for discovering prodromal biomarkers of Parkinson’s disease (PD). In this study, we aim to identify CSF candidate risk biomarkers of PD in individuals with LRRK2 mutation carriers....

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書誌詳細
出版年:Transl Neurodegener
主要な著者: Majbour, Nour K., Aasly, Jan O., Hustad, Eldbjørg, Thomas, Mercy A., Vaikath, Nishant N., Elkum, Naser, van de Berg, Wilma D. J., Tokuda, Takahiko, Mollenhauer, Brit, Berendse, Henk W., El-Agnaf, Omar M. A.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201744/
https://ncbi.nlm.nih.gov/pubmed/32375873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-020-00192-4
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