CSF total and oligomeric α-Synuclein along with TNF-α as risk biomarkers for Parkinson’s disease: a study in LRRK2 mutation carriers

BACKGROUND: Asymptomatic carriers of leucine-rich repeat kinase 2 (LRRK2) gene mutations constitute an ideal population for discovering prodromal biomarkers of Parkinson’s disease (PD). In this study, we aim to identify CSF candidate risk biomarkers of PD in individuals with LRRK2 mutation carriers....

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Detalhes bibliográficos
Publicado no:Transl Neurodegener
Main Authors: Majbour, Nour K., Aasly, Jan O., Hustad, Eldbjørg, Thomas, Mercy A., Vaikath, Nishant N., Elkum, Naser, van de Berg, Wilma D. J., Tokuda, Takahiko, Mollenhauer, Brit, Berendse, Henk W., El-Agnaf, Omar M. A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201744/
https://ncbi.nlm.nih.gov/pubmed/32375873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-020-00192-4
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