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Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging

Autophagy removes both functional and damaged intracellular macromolecules from cells via lysosomal degradation. Three autophagic mechanisms, namely macroautophagy, chaperone-mediated autophagy (CMA), and microautophagy, have been described in mammals. Studies in experimental systems have found macr...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Loeffler, David A., Klaver, Andrea C., Coffey, Mary P., Aasly, Jan O.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952035/
https://ncbi.nlm.nih.gov/pubmed/29867441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00130
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