Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage

Trauma is a leading cause of death worldwide with 5.8 million deaths occurring yearly. Almost 40% of trauma deaths are due to bleeding and occur in the first few hours after injury. Of the remaining severely injured patients up to 25% develop a dysregulated immune response leading to multiple organ...

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Udgivet i:Front Immunol
Main Authors: Aswani, Andrew, Manson, Joanna, Itagaki, Kiyoshi, Chiazza, Fausto, Collino, Massimo, Wupeng, Winston Liao, Chan, Tze Khee, Wong, W. S. Fred, Hauser, Carl J., Thiemermann, Chris, Brohi, Karim
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951958/
https://ncbi.nlm.nih.gov/pubmed/29867926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00891
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