Distinct Signalling Properties of Insulin Receptor Substrate (IRS)-1 and IRS-2 in Mediating Insulin/IGF-1 Action

Insulin/IGF-1 action is driven by a complex and highly integrated signalling network. Loss-of-function studies indicate that the major insulin/IGF-1 receptor substrate (IRS) proteins, IRS-1 and IRS-2, mediate different biological functions in vitro and in vivo, suggesting specific signalling propert...

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Detaylı Bibliyografya
Yayımlandı:Cell Signal
Asıl Yazarlar: Rabiee, Atefeh, Krüger, Marcus, Ardenkjær-Larsen, Jacob, Kahn, C. Ronald, Emanuelli, Brice
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951756/
https://ncbi.nlm.nih.gov/pubmed/29550500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.03.003
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