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Modular synthesis of dihydro-isoquinolines: palladium-catalyzed sequential C(sp(2))–H and C(sp(3))–H bond activation
An efficient synthesis of dihydro-isoquinolines via a Pd–catalyzed double C–H bond [a C(sp(2))–H and a C(sp(3))–H bond] activation/annulation (CHAA) reaction is presented. This methodology features a short reaction time, high atom economy (loss of H(2)O only) and the formation of a sterically less f...
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| Publicado no: | Chem Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5950195/ https://ncbi.nlm.nih.gov/pubmed/29861906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01482d |
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