Promiscuous activities of heterologous enzymes lead to unintended metabolic rerouting in Saccharomyces cerevisiae engineered to assimilate various sugars from renewable biomass

BACKGROUND: Understanding the global metabolic network, significantly perturbed upon promiscuous activities of foreign enzymes and different carbon sources, is crucial for systematic optimization of metabolic engineering of yeast Saccharomyces cerevisiae. Here, we studied the effects of promiscuous...

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Détails bibliographiques
Publié dans:Biotechnol Biofuels
Auteurs principaux: Yun, Eun Ju, Oh, Eun Joong, Liu, Jing-Jing, Yu, Sora, Kim, Dong Hyun, Kwak, Suryang, Kim, Kyoung Heon, Jin, Yong-Su
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950193/
https://ncbi.nlm.nih.gov/pubmed/29785207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-018-1135-7
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