Promiscuous activities of heterologous enzymes lead to unintended metabolic rerouting in Saccharomyces cerevisiae engineered to assimilate various sugars from renewable biomass

BACKGROUND: Understanding the global metabolic network, significantly perturbed upon promiscuous activities of foreign enzymes and different carbon sources, is crucial for systematic optimization of metabolic engineering of yeast Saccharomyces cerevisiae. Here, we studied the effects of promiscuous...

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Detalhes bibliográficos
Publicado no:Biotechnol Biofuels
Main Authors: Yun, Eun Ju, Oh, Eun Joong, Liu, Jing-Jing, Yu, Sora, Kim, Dong Hyun, Kwak, Suryang, Kim, Kyoung Heon, Jin, Yong-Su
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950193/
https://ncbi.nlm.nih.gov/pubmed/29785207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13068-018-1135-7
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