Small molecules capable of activating DNA methylation–repressed genes targeted by the p38 mitogen-activated protein kinase pathway

Regulation of gene expression by epigenetic modifications such as DNA methylation is crucial for developmental and disease processes, including cell differentiation and cancer development. Genes repressed by DNA methylation can be derepressed by various compounds that target DNA methyltransferases,...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Li, Xiang, Shang, Erchang, Dong, Qiang, Li, Yingfeng, Zhang, Jing, Xu, Shaohua, Zhao, Zuodong, Shao, Wei, Lv, Cong, Zheng, Yong, Wang, Hailin, Lei, Xiaoguang, Zhu, Bing, Zhang, Zhuqiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950019/
https://ncbi.nlm.nih.gov/pubmed/29559556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000757
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