Small molecules capable of activating DNA methylation–repressed genes targeted by the p38 mitogen-activated protein kinase pathway

Regulation of gene expression by epigenetic modifications such as DNA methylation is crucial for developmental and disease processes, including cell differentiation and cancer development. Genes repressed by DNA methylation can be derepressed by various compounds that target DNA methyltransferases,...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Li, Xiang, Shang, Erchang, Dong, Qiang, Li, Yingfeng, Zhang, Jing, Xu, Shaohua, Zhao, Zuodong, Shao, Wei, Lv, Cong, Zheng, Yong, Wang, Hailin, Lei, Xiaoguang, Zhu, Bing, Zhang, Zhuqiang
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2018
Sujets:
Gene Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5950019/
https://ncbi.nlm.nih.gov/pubmed/29559556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000757
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