Inhibitory effect of PDGF-BB and serum-stimulated responses in vascular smooth muscle cell proliferation by hinokitiol via up-regulation of p21 and p53

INTRODUCTION: Vascular smooth muscle cell (VSMC) proliferation plays a major role in the progression of vascular diseases. In the present study, we established the efficacy and the mechanisms of action of hinokitiol, a tropolone derivative found in Chamaecyparis taiwanensis, Cupressaceae, in relatio...

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Detalhes bibliográficos
Publicado no:Arch Med Sci
Main Authors: Li, Jiun-Yi, Liu, Chun-Ping, Shiao, Wei-Cheng, Jayakumar, Thanasekaran, Li, Yi-Shin, Chang, Nen-Chung, Huang, Shih-Yi, Hsieh, Cheng-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Termedia Publishing House 2018
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949921/
https://ncbi.nlm.nih.gov/pubmed/29765446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2018.75085
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