Antiproliferative Activity of Hinokitiol, a Tropolone Derivative, Is Mediated via the Inductions of p-JNK and p-PLCγ1 Signaling in PDGF-BB-Stimulated Vascular Smooth Muscle Cells

Abnormal proliferation of vascular smooth muscle cells (VSMCs) is important in the pathogenesis of vascular disorders such as atherosclerosis and restenosis. Hinokitiol, a tropolone derivative found in Chamacyparis taiwanensis, has been found to exhibit anticancer activity in a variety of cancers th...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Yang, Po-Sheng, Wang, Meng-Jiy, Jayakumar, Thanasekaran, Chou, Duen-Suey, Ko, Ching-Ya, Hsu, Ming-Jen, Hsieh, Cheng-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272725/
https://ncbi.nlm.nih.gov/pubmed/25961161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20058198
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