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Inhibitory mechanism of tranilast in human coronary artery smooth muscle cells proliferation, due to blockade of PDGF-BB-receptors

1. We have previously reported that tranilast, an anti-allergic drug, prevented the experimental intimal thickening in the rat and mouse femoral arteries and its effect may be exerted through the inhibition of vascular smooth muscle cell proliferation. However, its inhibitory mechanism has yet to be...

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Detaylı Bibliyografya
Asıl Yazarlar: Watanabe, Shinji, Matsuda, Akihisa, Suzuki, Yasuhiro, Kondo, Kazunao, Ikeda, Yasuhiko, Hashimoto, Hisakuni, Umemura, Kazuo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2000
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572058/
https://ncbi.nlm.nih.gov/pubmed/10807667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703285
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