Inhibitory mechanism of tranilast in human coronary artery smooth muscle cells proliferation, due to blockade of PDGF-BB-receptors

1. We have previously reported that tranilast, an anti-allergic drug, prevented the experimental intimal thickening in the rat and mouse femoral arteries and its effect may be exerted through the inhibition of vascular smooth muscle cell proliferation. However, its inhibitory mechanism has yet to be...

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Bibliographische Detailangaben
Hauptverfasser: Watanabe, Shinji, Matsuda, Akihisa, Suzuki, Yasuhiro, Kondo, Kazunao, Ikeda, Yasuhiko, Hashimoto, Hisakuni, Umemura, Kazuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2000
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Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572058/
https://ncbi.nlm.nih.gov/pubmed/10807667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703285
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