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Multiple ligand binding sites regulate the Hedgehog signal transducer Smoothened in vertebrates

The Hedgehog (Hh) pathway plays a central role in the development of multicellular organisms, guiding cell differentiation, proliferation and survival. While many components of the vertebrate pathway were discovered two decades ago, the mechanism by which the Hh signal is transmitted across the plas...

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Detaylı Bibliyografya
Yayımlandı:Curr Opin Cell Biol
Asıl Yazarlar: Byrne, Eamon FX, Luchetti, Giovanni, Rohatgi, Rajat, Siebold, Christian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5949240/
https://ncbi.nlm.nih.gov/pubmed/29268141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2017.10.004
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