Implications of fALS Mutations on Sod1 Function and Oligomerization in Cell Models

Among the familial forms of amyotrophic lateral sclerosis (fALS), 20% are associated with the Cu,Zn-superoxide dismutase (Sod1). fALS is characterized by the accumulation of aggregated proteins and the increase in oxidative stress markers. Here, we used the non-invasive bimolecular fluorescence comp...

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Pubblicato in:Mol Neurobiol
Autori principali: Brasil, Aline A., Magalhães, Rayne S. S., De Carvalho, Mariana D. C., Paiva, Isabel, Gerhardt, Ellen, Pereira, Marcos D., Outeiro, Tiago F., Eleutherio, Elis C. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948255/
https://ncbi.nlm.nih.gov/pubmed/28884318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-017-0755-4
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