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Optical Control of Muscle Function by Transplantation of Stem Cell–Derived Motor Neurons in Mice

Damage to the central nervous system caused by traumatic injury or neurological disorders can lead to permanent loss of voluntary motor function and muscle paralysis. Here, we describe an approach that circumvents central motor circuit pathology to restore specific skeletal muscle function. We gener...

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Publicat a:Science
Autors principals: Bryson, J. Barney, Machado, Carolina Barcellos, Crossley, Martin, Stevenson, Danielle, Bros-Facer, Virginie, Burrone, Juan, Greensmith, Linda, Lieberam, Ivo
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947756/
https://ncbi.nlm.nih.gov/pubmed/24700859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1248523
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