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Optical Control of Muscle Function by Transplantation of Stem Cell–Derived Motor Neurons in Mice

Damage to the central nervous system caused by traumatic injury or neurological disorders can lead to permanent loss of voluntary motor function and muscle paralysis. Here, we describe an approach that circumvents central motor circuit pathology to restore specific skeletal muscle function. We gener...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Bryson, J. Barney, Machado, Carolina Barcellos, Crossley, Martin, Stevenson, Danielle, Bros-Facer, Virginie, Burrone, Juan, Greensmith, Linda, Lieberam, Ivo
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947756/
https://ncbi.nlm.nih.gov/pubmed/24700859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1248523
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