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Optical Control of Muscle Function by Transplantation of Stem Cell–Derived Motor Neurons in Mice

Damage to the central nervous system caused by traumatic injury or neurological disorders can lead to permanent loss of voluntary motor function and muscle paralysis. Here, we describe an approach that circumvents central motor circuit pathology to restore specific skeletal muscle function. We gener...

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Dettagli Bibliografici
Pubblicato in:Science
Autori principali: Bryson, J. Barney, Machado, Carolina Barcellos, Crossley, Martin, Stevenson, Danielle, Bros-Facer, Virginie, Burrone, Juan, Greensmith, Linda, Lieberam, Ivo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947756/
https://ncbi.nlm.nih.gov/pubmed/24700859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1248523
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