Next‐Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma

BACKGROUND. Because imaging has a high sensitivity to diagnose hepatocellular carcinoma (HCC) and tissue biopsies carry risks such as bleeding, the latter are often not performed in HCC. Blood‐derived circulating tumor DNA (ctDNA) analysis can identify somatic alterations, but its utility has not be...

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Dades bibliogràfiques
Publicat a:Oncologist
Autors principals: Ikeda, Sadakatsu, Tsigelny, Igor F., Skjevik, Åge A., Kono, Yuko, Mendler, Michel, Kuo, Alexander, Sicklick, Jason K., Heestand, Gregory, Banks, Kimberly C., Talasaz, AmirAli, Lanman, Richard B., Lippman, Scott, Kurzrock, Razelle
Format: Artigo
Idioma:Inglês
Publicat: AlphaMed Press 2018
Matèries:
Hepatobiliary
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5947459/
https://ncbi.nlm.nih.gov/pubmed/29487225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0479
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